Fenofibrate-d6 is the deuterium labeled version of Fenofibrate. Fenofibrate is recognized as a selective PPARα agonist with an EC50 of 30 μM. It also acts as an inhibitor of various human cytochrome P450 isoforms, demonstrating IC50s of 0.2, 0.7, 9.7, 4.8, and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated, which can affect the pharmacokinetic and metabolic profiles of drugs.